selective inhibition वाक्य
उदाहरण वाक्य
मोबाइल
- Marked differences exist among NSAIDs in their selective inhibition of the two subtypes of cyclooxygenase, COX-1 and COX-2.
- MZB exerts its activity through selective inhibition of inosine monophosphate synthetase and guanosine monophosphate synthetase, resulting in the complete inhibition of guanine nucleotide synthesis without incorporation into nucleotides.
- Farinomalein has shown potent and selective inhibition ( 0.15-5 ?g / disk ) against eight isolates of plant pathogenic " Phytophthora sojae ".
- Ca v 1.3 channels belong to the Ca v 1 family, which form L-type calcium currents and are sensitive to selective inhibition by dihydropyridines ( DHP ).
- May, M . J ., " et al . ", Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex.
- A para-sulfamoylphenyl at position 1 of the pyrazole was found to have a higher potency for COX-2 selective inhibition than a para-methoxyphenyl ( see structures 1 and 2, below ).
- The most significant difference between the isoenzymes, which allows for selective inhibition, is the substitution of isoleucine at position 523 in " COX-1 " with valine in " COX-2 ".
- Research indicates that the active site environment of Plasmodium SHMTs ( PSHMTs ) differ from that of human cytosolic SHMT quite a bit, allowing for the possibility of selective inhibition of PSHMT and, thus, the treatment of malaria infections.
- The natural chemical farinomalein ( a metabolite from entomopathogenic fungus " Paecilomyces farinosus " ) has shown potent and selective inhibition ( 0.15-5 ?g / disk ) against eight isolates of plant pathogenic " Phytophthora sojae ".
- The underlying mechanism for the deleterious effect proposes that endothelial cells lining the microvasculature in the body express COX-2, whose selective inhibition results in levels of prostaglandin I2 ( PGI2, prostacyclin ) down-regulated relative to thromboxane ( since COX-1 in platelets is unaffected ).
- MAO-A inhibition reduces the breakdown of primarily serotonin, norepinephrine, and dopamine; selective inhibition of MAO-A allows for tyramine to be metabolised via MAO-B . Agents that act on serotonin if taken with another serotonin-enhancing agent may result in a potentially fatal interaction called serotonin syndrome or with irreversible and unselective inhibitors ( such as older MAOIs ), of MAO a hypertensive crisis as a result of tyramine food interactions is particularly problematic with older MAOIs.
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